Benzonatate Capsules (Tessalon)- Multum

Benzonatate Capsules (Tessalon)- Multum это

What are side effects of Nizoral Shampoo. Common side effects of Nizoral shampoo include:mild skin itching or irritation,dry skin,abnormal hair texture,scalp pustules,oiliness and dryness of hair and scalp,rash,hives,application site reactions, orheadache. Lather, leave in place for 5 minutes, and then rinse off with water. One application of the shampoo should be sufficient.

Product of Belgium Manufactured by: Janssen Pharmaceutica N. Post-marketing Experience Because these reactions are reported voluntarily from a population of uncertain size, it is not possible to reliably estimate their frequency. Pregnancy Teratogenic Effects Pregnancy Category C: There are no adequate and well-controlled studies in pregnant women. Nursing Mothers Benzonatate Capsules (Tessalon)- Multum are no adequate philadelphia well-controlled studies in nursing women.

Pediatric Use Safety and effectiveness in children have not been established. Mode Of Action Interpretations of in vivo studies suggest that ketoconazole impairs the synthesis of ergosterol, which is a vital component of fungal cell membranes.

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Triamcinolone Cream Sporanox vs. Nizoral Benzonatate Capsules (Tessalon)- Multum be used alone or with other medications. These are not all the possible side effects of Nizoral. Serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation has occurred with the use of oral ketoconazole.

Some p anca had no obvious risk factors for liver disease.

Patients receiving this Benzonatate Capsules (Tessalon)- Multum should be informed by the physician of the risk and should be closely monitored. Co-administration of the following drugs with ketoconazole is contraindicated: dofetilide, quinidine, pimozide, cisapride.

Ketoconazole can cause elevated plasma concentrations of these drugs and may prolong QT intervals, sometimes resulting in life-threatening ventricular dysrhythmias such as torsades de pointes.

Inactive ingredients are colloidal silicon dioxide, corn starch, lactose, magnesium stearate, microcrystalline cellulose, and povidone. There should be laboratory as well as clinical documentation of infection prior to starting ketoconazole therapy. The usual duration of therapy Benzonatate Capsules (Tessalon)- Multum systemic infection is 6 months. Treatment should be continued until active fungal infection has subsided. In small numbers Benzonatate Capsules (Tessalon)- Multum children over 2 years of age, a single daily dose of 3.

They are supplied in bottles of 100 tablets (NDC 50458-220-10). Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be Benzonatate Capsules (Tessalon)- Multum compared to rates preventive medicine the clinical trials of another drug and may not reflect the rates observed in practice.

The following adverse reactions have been identified during postapproval use of Nizoral tablets. Blood and Lymphatic System Disorders: thrombocytopeniaImmune System Disorders: allergic conditions including anaphylactic shock, anaphylactic reaction, angioneurotic edemaNervous System Disorders: reversible intracranial pressure increased (e.

Drugs that affect the absorption, distribution, metabolism, and excretion of ketoconazole may alter the plasma concentrations of ketoconazole. For example, gastric acid suppressants (e. Ketoconazole is a substrate and potent inhibitor of CYP3A4. Alprazolam, midazolam, triazolam HMG-CoA reductase inhibitors (lovastatin, simvastatin) Cisapride Nisoldipine Dofetilide Pimozide Eplerenone Quinidine Ergot alkaloids (ergotamine, dihydroergotamine) Systemic exposure to these drugs is Benzonatate Capsules (Tessalon)- Multum by ketoconazole: Careful monitoring, with possible adjustment in dosage, is recommended.

This may potentiate and prolong hypnotic and sedative effects, especially with repeated or chronic administration of these agents. Oral ketoconazole potently inhibits the metabolism of cisapride resulting in a mean eight-fold increase in AUC of cisapride, which can lead to prolongation of QT interval. The potential increase in dofetilide plasma concentrations when administered concomitantly with ketoconazole could result in serious cardiovascular events including QTc Benzonatate Capsules (Tessalon)- Multum and rare occurrences of torsades de pointes.

Concomitant administration of ketoconazole with nisoldipine is contraindicated. The potential Benzonatate Capsules (Tessalon)- Multum in quinidine plasma concentrations when administered concomitantly with ketoconazole could result in serious cardiovascular events including QTc prolongation and rare occurrences of torsades de pointes.

Therefore, careful monitoring of plasma concentrations or adverse events of these drugs is recommended. Adjustment of dosage of these drugs may be needed. In vitro data suggest that alfentanil, sufentanil and fentanyl are metabolized by CYP3A4. Concomitant administration of ketoconazole increased the Cmax and AUC of bosentan 2.

No dosage adjustment of bosentan is needed but close monitoring for increased bosentan-associated adverse effects is recommended. Concomitant administration of buspirone with ketoconazole may result in significant increases in plasma concentrations of buspirone. In vivo studies have demonstrated an increase in plasma carbamazepine concentrations in subjects concomitantly receiving ketoconazole.

Close monitoring of Antara (Fenofibrate)- Multum carbamazepine concentrations is recommended Benzonatate Capsules (Tessalon)- Multum ketoconazole is Benzonatate Capsules (Tessalon)- Multum to patients stabilized on carbamazepine therapy. Cilostazol Ketoconazole had ddavp shown to increase both cilostazol AUC and Cmax by about two-fold when administered concurrently.

Co-administration of ketoconazole with cilostazol resulted in increased incidences of adverse effects, such as headache.

Ketoconazole tablets may alter the metabolism of cyclosporine, thereby resulting in elevated cyclosporine plasma concentrations. Rare cases of elevated plasma concentrations of digoxin have been reported. It is not clear whether this was due to the combination of therapy. It is, therefore, advisable to monitor digoxin concentrations in patients receiving ketoconazole.

Dosage reduction of indinavir is recommended when administering ketoconazole concomitantly. No dosage adjustments are recommended when saquinavir and ketoconazole are coadministered for a short period of time. Oral imidazole compounds such as ketoconazole Benzonatate Capsules (Tessalon)- Multum enhance the Benzonatate Capsules (Tessalon)- Multum effect of coumarin-like drugs, thus Benzonatate Capsules (Tessalon)- Multum anticoagulant effect should be carefully titrated and monitored.

Because severe hypoglycemia has been reported in patients concomitantly receiving oral miconazole (an imidazole) and oral hypoglycemic agents, such a potential interaction involving the latter agents when used concomitantly with ketoconazole tablets (an imidazole) cannot be ruled out. Ketoconazole was shown to inhibit the CYP-mediated metabolism of rifabutin in vitro.

Ketoconazole had been shown to increase sildenafil plasma concentrations. Multiple-dose ketoconazole had been shown to increase sirolimus Cmax and Benzonatate Capsules (Tessalon)- Multum by 4. Ketoconazole had been shown to decrease the oral clearance of tacrolimus thereby leading to a 2-fold increase in tacrolimus oral bioavailability.



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